We define the object detection from imagery problem as estimating a very large but extremely sparse bounding box dependent probability distribution. Subsequently we develop a novel sparse distribution estimation scheme called Directed Sparse Sampling, and employ it in a single end-to-end CNN based detection model. This methodology extends and formalizes previous state-of-the-art detection models with an additional emphasis on high evaluation rates and reduced manual engineering. The resulting model is scene adaptive, does not require manually defined reference bounding boxes and produces highly competitive results on MSCOCO, Pascal VOC 2007 and Pascal VOC 2012 with real-time evaluation rates. Further analysis suggests our model performs particularly well when finegrained object localization is desirable. We argue that this advantage stems from the much larger set of available regions-of-interest relative to other methods.