We present an exhaustive investigation of recent Deep Learning architectures, algorithms, and strategies for the task of document image classification to finally reduce the error by more than half. Existing approaches, such as the DeepDocClassifier, apply standard Convolutional Network architectures with transfer learning from the object recognition domain. The contribution of the paper is threefold: First, it investigates recently introduced very deep neural network architectures (GoogLeNet, VGG, ResNet) using transfer learning (from real images). Second, it proposes transfer learning from a huge set of document images, i.e. 400,000 documents. Third, it analyzes the impact of the amount of training data (document images) and other parameters to the classification abilities. We use two datasets, the Tobacco-3482 and the large-scale RVL-CDIP dataset. We achieve an accuracy of 91.13% for the Tobacco-3482 dataset while earlier approaches reach only 77.6%. Thus, a relative error reduction of more than 60% is achieved. For the large dataset RVL-CDIP, an accuracy of 90.97% is achieved, corresponding to a relative error reduction of 11.5%.